





















$795,000
622 N Main Street, Independence, MO 64050
622 N Main Street, Independence, MO 64050 is an active 63,000-square-foot business listed for $795,000. MLS #2591863.
Highlights
About this home
Adaptive reuse opportunity formally known as St. Mary's Highschool is located just off the Independence square in an opportunity zone and could serve several different purposes including multi family. The roof was recently replaced in the last 4-5 years, Asbestos's has been abated, the property is eligible for…
Property Details
Interior
Bedrooms & bathrooms
- Full bathrooms: 0
Interior area
- Total interior livable area: 63,000 sqft
Property
Parking
- Parking features: Parking Lot
Lot
- Size: 1.45 Acres
Construction
Type & style
- Home type: Business Opportunity
- Architectural style: Business
Condition
- Year built: 1975
- Age: 41-50 Years
HOA and Amenities
No HOA on this home.
Nearby schools
Price history
Tax
- Annual tax amount: $11,124 / yr
HouseLoop Mortgage Calculator
$5,549
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Similar listingsand the Independence market
Look throughoutIndependence, Missouri
There are currently 366 homes for sale in Independence, with 203 under contract.
Independence sits in Jackson County, which covers 51 zip codes and 2,778 homes for sale.
Sources — listings and prices: Heartland MLS as distributed by MLS GRID, as of September 14, 2026 · analysis: HouseLoop.
Offer Insights
Choose an offer strength
$795,000 – $810,105
Market Estimate
64050 · ZIP · sell-to-list 102%
$787,000 – $811,000
This home's area
Popular searches in Independence, MO
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Independence, MO homes for sale by zip code for sale · median sale · days to contract
HouseLoop analysis of Heartland MLS data distributed by MLS GRID · trailing 12 months. Median sale price: the median closed price among sold homes in that zip over the same window.
Counties homes for sale · median list price
Listed by Asher Real Estate LLC
Listed December 11, 2025 12:20 PM · Source: Heartland MLS as distributed by MLS GRID · MLS #2591863
HouseLoop last checked:
Listing updated:
$795,000
622 N Main Street, Independence, MO 64050
About this home
Adaptive reuse opportunity formally known as St. Mary's Highschool is located just off the Independence square in an opportunity zone and could serve several different purposes including multi family. The roof was recently replaced in the last 4-5 years, Asbestos's has been abated, the property is eligible for…
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Property Details
Interior
Bedrooms & bathrooms
- Full bathrooms: 0
Interior area
- Total interior livable area: 63,000 sqft
Property
Parking
- Parking features: Parking Lot
Lot
- Size: 1.45 Acres
Construction
Type & style
- Home type: Business Opportunity
- Architectural style: Business
Condition
- Year built: 1975
- Age: 41-50 Years
HOA and Amenities
No HOA on this home.
Nearby schools
Price history
Tax
- Annual tax amount: $11,124 / yr
HouseLoop Mortgage Calculator
$5,549
Offer Insights
Choose an offer strength
$795,000 – $810,105
Market Estimate
64050 · ZIP · sell-to-list 102%
$787,000 – $811,000
Already own a home?What's your home worth?
Enter your address to unlock your free HouseLoop Home Value Report — Zillow, Redfin, our HouseLoop value, the demand for it, and what the market's doing around it.
Similar listingsand the Independence market
Look throughoutIndependence, Missouri
There are currently 366 homes for sale in Independence, with 203 under contract.
Independence sits in Jackson County, which covers 51 zip codes and 2,778 homes for sale.
Sources — listings and prices: Heartland MLS as distributed by MLS GRID, as of September 14, 2026 · analysis: HouseLoop.
This home's area
Popular searches in Independence, MO
Search nearby cities
Independence, MO homes for sale by zip code for sale · median sale · days to contract
HouseLoop analysis of Heartland MLS data distributed by MLS GRID · trailing 12 months. Median sale price: the median closed price among sold homes in that zip over the same window.
Counties homes for sale · median list price
Listed by Asher Real Estate LLC
Listed December 11, 2025 12:20 PM · Source: Heartland MLS as distributed by MLS GRID · MLS #2591863
HouseLoop last checked:
Listing updated:








